Buy Tetracaine hcl online. Tetracaine, also known as amethocaine, is an ester local anesthetic used to numb the eyes, nose, or throat.[2] It may also be applied to the skin before starting an intravenous (injection) to decrease pain from the procedure.[3] Typically it is applied as a liquid to the area.[2] Onset of effects when used in the eyes is within 30 seconds and last for less than 15 minutes.
Common side effects include a brief period of burning at the site of use.[2] Allergic reactions may uncommonly occur.[4] Long-term use is generally not recommended as it may slow healing of the eye.[2] It is unclear if use during pregnancy is safe for the baby.[2] Tetracaine is in the ester-type local anesthetic family of medications.[4] It works by blocking the sending of nerve impulses.[2]
Tetracaine was patented in 1930 and came into medical use in 1941.[5] It is on the World Health Organization’s List of Essential Medicines
GK4286 Tetracaine hydrochloride
4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester; Amethocaine hydrochloride; 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride; 2-(Dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride; Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride; 2-(Dimethylamino)ethyl p-(butylamino)benzoate monohydrochloride
Tetracaine Hydrochloride Or Tetracaine Hcl Powder Raw Material, API CAS 136-47-0
Tetracaine Hydrochloride or Tetracaine Hcl Powder Raw Material, API CAS 136-47-0 Product Name: Tetracaine Hydrochloride or Tetracaine Hcl CAS Number: 136-47-0 Characteristics: A white crystalline powder Assay: 99.0%~101.0% Tetracaine Hcl Formula: C15H25ClN2O2 Structure Formula: Standard: Package information: 25Kgs/Drum...
Product Name: Tetracaine Hydrochloride or Tetracaine Hcl
CAS Number: 136-47-0
Characteristics: A white crystalline powder
Assay: 99.0%~101.0% Tetracaine Hcl
Formula: C15H25ClN2O2
Structure Formula:
Standard:
Package information: 25Kg/Fiber Drum, Cardboard Drum, Paper Drum
KEY Words: Tetracaine Hydrochloride, Tetracaine Hcl API, Raw Material Powder
Description:
Tetracaine Hydrochloride is also called Tetracaine Hcl or sometimes is also known as amethocaine Hydrochloride. It is a local anesthetic, which belongs to the ester anesthetic group.
Tetracaine Hydrochloride is mainly used topically in ophthalmology and as an anti-pruritic. It is also used in spinal anesthesia area.
By recent biomedical research, Tetracaine Hcl can alter the function of calcium release channels (know as ryanodine receptors) that control the release of calcium from intracellular stores.
Tetracaine Hcl is an allosteric blocker of these channel function.
When it is in low concentrations: Tetracaine Hcl causes an initial inhibition of spontaneous calcium release events,
When it is in high concentrations: Tetracaine Hydrochloride blocks the release completely.
Together with other substances, Tetracaine Hcl is widely used in ear, nose & throat surgery. Moreover, in the emergency department, it is used to numb the surface rapidly. Especially when children injured their eyes, ear, or some other sensitive locations.
Tetracaine Hcl is on the WHO’s List of Essential Medicines.
——————————-
Description:
Tetracaine Hydrochloride, Tetracaine Hcl Powder Raw Material, API BP, EP, USP is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
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Application:
Tetracaine Hydrochloride, Tetracaine Hcl Powder Raw Material, API BP, EP, USP (Also known as amethocaine) is a potent local anesthetic of the ester group. It is mainly utilized topically in ophthalmology and as an anti-pruritic, and it has been used in spinal anesthesia.
In biomedical studies, Tetracaine Hydrochloride, Tetracaine Hcl Powder Raw Material, API BP, EP, USP is applied to alter the function of calcium release channels (ryanodine receptors) which control the release of calcium from intracellular stores. Tetracaine Hydrochloride, Tetracaine Hcl Powder Raw Material, API BP, EP, USP is an allosteric blocker of channel function. At low concentrations, Tetracaine Hydrochloride, Tetracaine Hcl Powder Raw Material, API BP, EP, USP will cause an initial inhibition of spontaneous calcium release events, while at high concentrations, it will block release completely.
Usage and applications: Tetracaine Hydrochloride, Tetracaine Hcl Powder Raw Material, API BP, EP, USP is widely applied for mucosal epidermal anesthesia, nerve tissue anesthesia, epidural anesthesia and Subarachnoid space anesthesia.
———————————
Alias: Tetracaine HCl; Amethocaine hydrochloride
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
Product Categories: API intermediates; Sodium channel; Amines; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals; Pharmaceutical intermediate; PONTOCAINE
———————————–
Other names:
Tetracaini hydrochloridum
Main indexes of Tetracaine Hydrochloride or Tetracaine Hcl
ITEM | SPECIFICATION | RESULTS |
Description Tetracaine Hcl | A white crystalline powder | white crystalline powder |
Identification Tetracaine Hydrochloride | To comply | Complies |
Appearance of solution | Clear and colourless | Complies |
pH | 4.5-6.5 | 5.4 |
Related Substance (By TLC) | To comply | Complies |
Heavy metals | 10 ppm | Complies |
Moisture(Water) | Not more than 2.0% | <2.0% |
Loss on drying | <1.0% | 0.30% |
Sulphated ash | <0.1% | 0.05% |
Assay (TLC) Tetracaine Hydrochloride | 99.0%~101.0% | 99.5% |
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Tetracaine Hydrochloride CAS 136-47-0 Product Description
Product Name: | Tetracaine hydrochloride |
Synonyms: | 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester,Ameth;Tetracaine (hydrochloride);Tetracaine HCl;MFCD00038912;curtacain;EINECS 205-248-5;PANTOCAINE;gingicainm;decicaine;anethaine;4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester,Amethocaine hydrochloride;anacel;butethanol;tonexol;decicain;menonasal |
CAS NO: | 136-47-0 |
Molecular Weight: | 300.82 |
Molecular Formula: | C15H25ClN2O2 |
Boiling Point: | 1202.1±65.0 °C at 760 mmHg |
Melting point: | 389.4ºC at 760 mmHg |
Density: | 1.1279 (rough estimate) |
Appearance: | White crystalline or crystalline powder |
Applications: | Local anaesthetics. Tetracaine hydrochloride [136-47-0] has a stronger local anaesthetic effect and greater toxicity than procaine. It can penetrate the mucosa and is mainly used for mucosal anaesthesia. |
Solubility: | Soluble in water, soluble in ethanol, insoluble in ether or benzene. |
Storage: | Refrigerator |
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What is tetracaine hydrochloride CAS 136-47-0?
Tetracaine eye drops are used to numb the eye before surgery, certain tests, or procedures. The eye drops are used to prevent pain during the procedure. Tetracaine belongs to the group of medicines called local anesthetics. It works by blocking the pain signals at the nerve endings in the eye.
what is tetracaine hydrochlorideCAS 136-47-0 used for
Tetracaine eye drops are used to numb the eye before surgery, certain tests, or procedures. The eye drops are used to prevent pain during the procedure. Tetracaine belongs to the group of medicines called local anesthetics. It works by blocking the pain signals at the nerve endings in the eye.
tetracaine hydrochloride CAS 136-47-0 how often
Patients will be instructed to use 1-2 drops of up to every 30 min for pain control over a 48 hour period with subsequent followup with the ophthalmologist.
tetracaine hydrochloride CAS 136-47-0 side effects
- Blurred vision.
- redness of the clear part of the eye.
- sensitivity to light.
- severe stinging in the eye.
- tearing.
- throbbing eye pain.
Tetracaine = 99 136-47-0
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Tetracaine hydrochloride (Amethocaine );≥99%; Tetracaine hydrochloride has … CAS Number: 136-47-0. Molecular Weight: 300.82. MDL number: MFCD00038912.
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Tetracaine Hydrochloride 136-47-0
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tetracaine HCl benzoic acid, 4-(butylamino)
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Supplier Sponsors ; Name: 2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride ; CAS Number: 136-47-0, Picture of molecule 3D/inchi ; Other(deleted CASRN): …
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Additional information on CAS 136-47-0. Catalogue No. PVE00376. CAS No. 136-47-0. Molecular Formula C15H24N2O2???HCl. Molecular Weight 300.82 g/mol. Parent drug …
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CAS: 136-47-0 – tetracaine hydrochloride
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CAS: 136-47-0 – tetracaine hydrochloride. Fórmula:C15H25ClN2O2. InChI:InChI=1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H …
Tetracaine Hydrochloride CAS 136-47-0
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Tetracaine Hydrochloride CAS 136-47-0 … Stability: Stable at normal temperatures and pressures. Storage Condition: Keep tightly closed. … Tetracaine (also known
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