Caffeine BP EP USP CAS 58-08-2 factory. China Caffeine BP EP USP CAS 58-08-2 factory, Supplier, Manufacturer in China.

Synonyms: 1,3,7-Trimethylxanthine

CAS Number: 58-08-2

Characteristics: White powder.

Molecular Formula: C8H10N4O2

Structure Formula:

Package: 25Kgs/Fiber Drum

KEY Words:

Caffeine BP EP USP CAS 58-08-2

Description:

Caffeine, a xanthine alkaloid compound, is a central nervous stimulant that temporarily dispels sleepiness and restores energy. Caffeine BP EP USP CAS 58-08-2 is clinically used to treat neurasthenia and coma resuscitation. Coffee, tea, soft drinks and energy drinks with caffeine are very popular, so caffeine is also the most widely used psychotropic drug in the world.

Caffeine BP EP USP CAS 58-08-2 is a plant alkaloid which can be found in many plants. As a natural insecticide, it paralyzes insects that eat caffeinated plants. The most commonly used caffeine-containing plants include coffee, tea and some cocoa. Other infrequent uses include Paraguayan holly and Guarana trees, commonly used for tea or energy drinks. Two aliases for caffeine: madeine and Guana factor evolved from these two plants.

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The main source of Caffeine BP EP USP CAS 58-08-2 in the world is coffee beans (seeds of coffee trees), and coffee beans are also the raw materials of coffee. The content of caffeine in coffee depends greatly on the variety of coffee beans and the method of making coffee. Even the content of Caffeine BP EP USP CAS 58-08-2 in coffee beans on the same tree is very different. Generally speaking, the caffeine content in a cup of coffee ranges from 40 mg to 100 mg. Deep roasted coffee generally contains less caffeine than shallow roasted coffee because roasting can reduce the caffeine content in coffee beans. Arabic coffee usually contains less Caffeine BP EP USP CAS 58-08-2 than medium fruit coffee. Coffee also contains trace theophylline, but no theobromine.

Tea is another important source of Caffeine BP EP USP CAS 58-08-2. The caffeine content of each cup of tea is generally only half of that of each cup of coffee, depending on the strength of the tea. Specific varieties of tea, such as black tea and oolong tea, have higher caffeine content than other teas. Tea contains a small amount of theobromine and a slightly higher theophylline than coffee. Tea production has a great impact on tea, but the color of tea can hardly indicate the content of Caffeine BP EP USP CAS 58-08-2. The caffeine content of Japanese green tea is much lower than that of many black tea, which contains almost no caffeine.

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Chocolate made from cocoa powder also contains a small amount of Caffeine BP EP USP CAS 58-08-2. Chocolate is a weak stimulant, mainly due to theobromine and theophylline. A typical 28g milk chocolate has about the same caffeine content as decaffeinated coffee.

Caffeine BP EP USP CAS 58-08-2 is also a common ingredient in soft drinks, such as cola, which was originally made from cola fruit. A bottle of soft drink usually contains 10 mg to 50 mg of caffeine. Energy drinks, contain 80 mg of caffeine per bottle. The Caffeine BP EP USP CAS 58-08-2 in these drinks is derived from the original ingredients they use or from additives derived from decaffeinated coffee, and is also chemically synthesized. Guarana, the basic ingredient of many energy drinks, contains a lot of caffeine and a little theobromine. The natural sustained-release excipient contains a small amount of theophylline.

Applications:

1. Caffeine BP EP USP CAS 58-08-2 is mainly used as stimulants, bitters and spices. It can be used in coke beverages and coffee drinks. The maximum allowable dosage is 200 mg/kg.

2. Caffeine BP EP USP CAS 58-08-2 has the function of stimulating the central nervous system such as refreshing and awakening the brain. Our country stipulates that it can be used for cola-type beverage with the maximum usage of 0.15g/kg.

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Certificate of Analysis (COA, TDS):

Name of Product	Caffeine BP EP USP CAS 58-08-2
Testing Item	Standard	Result
Appearance	White or almost white crystalline powder or crystals.	Complies
Identification A	Infrared Absorption	Complies
Identification B	The retention time of the Caffeine peak of the sample solution corresponds to that of the standard solution.	Complies
Solubility	Sparingly soluble in water, freely soluble in boiling water, slightly soluble in ethanol(96%). It dissolves in concentrated solution of alkali benzoates or salicylates.	Complies
Melting Range	234°C-239°C	234.5°C-238.5°C
Appearance of solution	Clear and colorless	Complies
Sulfates (SO4)	≤ 0.05%	0.02%
Heavy Metal	≤ 10ppm	< 10ppm
Loss on drying	≤ 0.5%	0.21%
Sulfated Ash	≤ 0.10%	0.03%
Single Impurity	≤ 0.10%	0.01%
Total Impurities	≤ 0.10%	0.015%
Purity (Assay)	98.5%-101.0% dried substance.	99.8%

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CAFFEINE POWDER 100% Anhydrous Pharma Grade

Caffeine is classified by the US Food and Drug Administration as generally recognised as safe (GRAS). Toxic doses, over 10 grams per day for an adult, are much higher than the typical dose of under 500 milligrams per day, A cup of coffee contains 80–175 mg of caffeine, depending on what “bean” (seed) is used and how it is prepared (e.g., drip, percolation, or espresso). Thus it requires roughly 50–100 ordinary cups of coffee to reach the toxic dose. However, pure powdered caffeine, which is available as a dietary supplement, can be lethal in tablespoon-sized amounts.

Suggested Use: An average cup of coffee contains approximately 100mg of caffeine – use this product accordingly.

Storage: Store in a cool dry place. Keep away from strong light and heat.

Caution: This product is PURE CAFFEINE – care must be taken as small amounts can be very potent. Using a micro weighing-balance of high accuracy, is strongly recommended. Avoid prolonged exposure to skin. Do not inhale, and avoid contact with mucous membranes and eyes.

WARNINGS: Keep out of the reach of young children. Do not exceed the recommended daily dose. Food supplements should not be used as a substitute for a varied and balanced diet. Do not take during pregnancy or for prolonged periods without consulting a doctor.

Content	Standard	Results
Appearance	White or almost white, crystalline powder (BP) or silky, white or almost white, crystals	White crystalline powder
IdentificationA.    Melting pointB.    Infrared AbsorptionC.    Loss on drying	234-239oC (BP)Conforms to the caffeine reference spectrum (BP)See Tests (BP)	236.2-237.0oCPassPass
Appearance on solution	Clear, colourless (BP)	Pass
Heavy metals	≤20ppm (BP)	<10ppm
Sulphates	≤500ppm (BP)	<500ppm
Related substances
Each impurity A, B ,C, D,E, F	≤0.10% (BP)	<0.10%
Unspecified impurities	≤0.10% (BP)	<0.10%
Total impurities	≤0.1% (BP)	<0.1%
Acidity	Not more than 0.2 ml of 0.01M sodium hydroxide (BP)	<0.2ml
Organic impurities
Individual impurities	≤0.1% (USP)	<0.1%
Total impurities	≤0.1% (USP)	<0.1%
Loss on drying	≤0.5% (BP)	0.10%
Residue on ignition	≤0.1% (USP)	0.05%
Assay	98.5%-101.0% (USP)	99.8%

Conclusion: The above product conforms to BP2015, USP38 requirement on Caffeine.